The Greenville Zoo, located in Greenville, South Carolina, has been designated one of the top ten small USA Zoos. Greenville Zoo is west off highway I-385, exit 42 to 150 Cleveland Park Dr. in Cleveland Park, following signs. Fourteen landscaped acres feature outdoor habitats with African elephants, primates, a red panda and exotic cats, including a white tiger. The reptile exhibit houses a 75-pound python. Picnicing is permitted. Food is available. Allow 2 hours minimum.